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Sodium thiosulfate is one of the few know substances that will dissolve silver bromide. As such it is universally used in modern photographic procedures.
In this process known as "fixation," the unexposed silver bromide is dissolved in the sodium thiosulfate by combining with it to form soluble complex thiosulfates of silver and sodium.
Always begin with water of at least 90°F/32°C when mixing the crystalline form. Use 64% of the anhydrous salt as a substitute for crystalline hypo.