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The ASUS M5A78L-M LE/USB3 Micro ATX Motherboard is designed to fit into a smaller-sized chassis so you can build a mini PC system with an AMD processor. It sports an AMD AM3+ socket, which lets you use an AMD FX, Phenom II, Athlon II, or Sempron 100 series processor. It comes with two memory slots that supports up to 16GB of DDR3 1866 MHz RAM modules. To deliver visuals, ASUS has built this motherboard to utilize your APU processor with integrated graphics or dedicated graphics card connected via the PCIe 2.0 x16 slot. When using integrated graphics, you can connect your monitor to the motherboard's DVI and VGA ports.
This motherboard comes equipped with four SATA 3 Gb/s ports along with RAID support to create reliable data storage for your system. For connecting external storage and other peripherals, it has two PS/2, two USB 3.0, four USB 2.0, and three 3.5mm audio ports as well as a serial COM port. Networking is accomplished with the built-in Gigabit Ethernet controller and RJ-45 jack. Moreover, audio is provided with an integrated Realtek ALC887 codec. ASUS also gives you a PCIe 2.0 x1 slot and a PCI slot.
AMD Socket AM3+
This motherboard is compatible with AMD AM3+ multi-core processors that have L3 cache such as AMD's FX, Phenom II, Athlon II, and Sempron 100 series of processors. It supports dual-channel DDR3 memory and offers a data transfer rate up to 5200 MT/s via a HyperTransport 3.0 based system bus. It also supports AMD CPUs in the 32nm manufacturing process and delivers better overclocking capabilities with less power consumption.
The ASUS EPU has been upgraded to a 4-engine version, which provides system power savings by detecting current PC loadings and moderating power intelligently in real-time. The EPU automatically offers appropriate power usage for the CPU, VGA card, hard drives, and CPU cooler fan—helping you save power and money.
ASUS Anti-Surge Protection
The anti-surge protection design detects overvoltage conditions and prevents voltage surges from spreading in real time. It also actively cuts off the overvoltage supply to protect the system.
Real-time over voltage detection
Active protection against potential damage to your motherboards and systems
The low-radiation design shields you from harmful electromagnetic exposure by eliminating 50% of radiation.
Radiation deduction design minimizes harmful electromagnetic radiation output with a circuit design to cancel electrical charge
The radiation moat design effectively blocks radiation to prevent discharge spread
Electrostatic discharge can happen while plugging or unplugging USB peripherals, causing damage to the computer. To provide a more reliable computing environment, ASUS's ESD guards clamp the ESD voltage and shunt the majority of the ESD current away.
ASUS Core Unlocker simplifies the activation of a latent AMD CPU with just a simply key. Without performing complicated BIOS changes, you can experience an instant performance boost by simply unlocking the extra cores.
ASUS Fan Xpert allows you to adjust CPU and chassis fan speeds accordingly to your PC's loading and to different ambient temperatures caused by the climate conditions in various geographic regions. It comes with useful profiles that offer flexible controls of the fan's speed to achieve a quiet and cool environment.
With a few clicks and a USB flash drive, you can update the BIOS without entering into the operating system using a user-friendly BIOS update utility.
8-Channel High-Definition Audio
The onboard 8-channel HD audio (previously codenamed Azalia) codec enables high-quality 192KHz/24-bit audio output, a jack-sensing feature, retasking functions, and multi-streaming technology that simultaneously sends different audio streams to different destinations. You can talk to your partners using your headset while playing multi-channel network games.
The motherboard is European Union´s Energy-related Products (ErP) ready, which requires products to meet certain energy efficiency requirements in regards to energy consumption. This is in line with the ASUS vision of creating environmentally-friendly and energy-efficient products through design and innovation that reduce the carbon footprint of products and thus mitigate ecological impact.
Software Included on Support Disc
ASUS PC Probe II
Anti-virus software (OEM version)
In the Box
ASUS M5A78L-M LE/USB3 Micro ATX Motherboard
SATA 3 Gb/s Cables
Limited 3-Year Warranty
Table of Contents
AMD AM3+ FX/Phenom II/Athlon II/Sempron 100 series of processors Supports CPU up to 125 W AMD Cool 'n' Quiet technology
Integrated ATI Radeon HD 3000 GPU - Supports DVI with a max. resolution of 2560 x 1600 @ 60 Hz - Supports RGB with a max. resolution of 2560 x 1440 @ 75 Hz Maximum shared memory of 1024 MB Hybrid CrossFireX support Supports DirectX 10
1 x PCIe 2.0 x16 1 x PCIe 2.0 x1 1 x PCI
4 x SATA 3 Gb/s ports (blue) Supports RAID 0, 1, 10, and JBOD
Realtek 8111GR Gigabit LAN controller
Realtek ALC887 8-channel High Definition audio CODEC - Audio Shielding: ensures precision analog/digital separation and greatly reduced multi-lateral interference - Dedicated Audio PCB Layers: separate layers for left and right channels guard the sensitive audio signals - Premium Japanese-made Audio Capacitors: provide warm, natural, and immersive sound with clarity and fidelity
8 x USB 2.0/1.1 (4 x ports at back panel, supports 4 at mid-board)
ASMedia ASM1042 controller : 2 x USB 3.0 ports
ASUS Power Design: - ASUS EPU
ASUS Exclusive Features: - Anti-Surge - Low EMI Solution
ASUS Quiet Thermal Solution: - ASUS Fan Xpert
ASUS EZ DIY : - ASUS CrashFree BIOS 3 - ASUS EZ Flash 2 - ASUS MyLogo 2
100% All High-quality Conductive Polymer Capacitors
Back I/O Ports
1 x PS/2 keyboard (purple) 1 x PS/2 mouse (green) 1 x DVI 1 x D-Sub 1 x LAN (RJ45) 2 x USB 3.0 (blue) 4 x USB 2.0 1 x COM 3 x Audio
Internal I/O Ports
2 x USB 2.0 connectors support additional 4 USB 2.0 ports 4 x SATA 3 Gb/s connectors 1 x CPU Fan connector 1 x 24-pin EATX Power connector 1 x 4-pin ATX 12V Power connector 1 x Front panel audio connector (AAFP) 1 x Internal speaker connector 1 x System panel
16 Mb Flash ROM, AMI BIOS , PnP, DMI v2.0, WfM2.0, SM BIOS V2.5, ACPI V3.0a