The Contour Design Unimouse connects to a computer wirelessly and has four adjustable features that enable you to use it like a typical mouse or in a vertical handshake position. The palm section of the Unimouse can tilt from 35 to 70 degrees to create a comfortable mousing experience. Your thumb is also supported after the adjustment process with a thumb rest, which can pivot 35 degress in either direction as well as slide in or out and forward or backward.