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The carbon gray Uptown Laptop TSA-Friendly Backpack from Timbuk2 holds up to a 17" MacBook Pro in its rear compartment. There's also a separate space for your iPad and other electronics. The pack lays flat when open revealing the laptop compartment. This will save you time and effort when passing through security checkpoints.
The main zippered compartment holds the bulk of your gear. There is a zippered organizer panel for small items and a top zippered compartment for sunglasses and additional personals. The side of the pack has a stretchable water bottle/U-lock pocket. Included with the bag is a Vista loop for a bicycle blinking light that will help you be seen in marginal light.
The computer compartments are lined with padded tricot to avoid scratching your equipment. The back panel is ventilated for breathability and the backpack straps are adjustable. A sternum strap helps keep the pack stabilized while you're on the move. The pack is made from water-resistant ripstop nylon with ballistic nylon on the back. A bottle opener is attached to a strap inside the pack.